Preheat oven to 425 degrees F. Line a large sheet pan with parchment or lightly oil it.
Season: in a large bowl, toss chicken, peppers, and onion with olive oil, chili powder, cumin, paprika, garlic powder, onion powder, salt, and pepper.
Spread: arrange mixture in a single layer on the sheet pan with some space between pieces.
Roast: bake 20 to 25 minutes, tossing once halfway, until chicken is cooked through and vegetables are browned at the edges.
Finish: squeeze lime juice over the pan, warm tortillas, and serve with toppings.